1640s, "notably pointed," from point (n.) + -y (2). Insult pointy-head for one deemed overly intellectual, attested by 1971, was popularized, if not coined, by U.S. politician George Wallace in his 1972 presidential run. In earlier slang (late 19c.) pointy meant "terse, well-put, pithy."
pointer
pointillism
pointing
pointless
point-to-point
pointy
poise
poison
poisoner
poisonous
poisonwood