1610s, from Late Latin pylorus "the lower orifice of the stomach," from Greek pyloros, literally "gatekeeper, porter," from pyle "gate" (see pylon) + ouros "watcher, guardian," from PIE root *wer- (3) "perceive, watch out for." Related: Pyloric.
pyelo-
Pygmalion
pygmy
pyjamas
pylon
pylorus
pyo-
pyogenic
Pyongyang
pyracanth
pyramid