1801, from French saponification, from saponifier, from Modern Latin saponificare, from sapon- "soap" (see soap (n.)) + -ficare, combining form of Latin facere "to make" (from PIE root *dhe- "to set, put").
sap
sapid
sapience
sapient
sapling
saponification
saponify
sapper
Sapphic
sapphire
Sapphism