1690s, "spark, glimmer," hence "least particle, trace," from figurative use of Latin scintilla "particle of fire, spark, glittering speck, atom," probably from PIE *ski-nto-, from root *skai- "to shine, to gleam" (source also of Gothic skeinan, Old English scinan "to shine;" see shine (v.)).
scientist
Scientology
scilicet
Scilly
scimitar
scintilla
scintillate
scintillation
sciolism
sciolist
sciomancy