1560s, from Middle French scirrheux (16c., Modern French squirreux), from Modern Latin scirrhosus, from Latin scirros "a hard swelling, tumor," from Greek skirrhos "hard tumor," from skiros (adj.) "hard," of unknown origin.
sciolism
sciolist
sciomancy
scion
sciophobia
scirrhous
scission
scissor
scissors
SCLC
sclera