"gentile girl," in Jewish culture, dismissive or disparaging, 1892, from Yiddish shikse, from Hebrew siqsa, from sheqes "a detested thing" + fem. suffix -a.
shih-tzu
Shiism
shiitake
Shiite
Shikoku
shiksa
shill
shillelagh
shilling
shilly-shally
Shiloh