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shut-in (n.)

"person confined from normal social intercourse," 1904, from the verbal phrase, from shut (v.) + in (adv.).

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Definitions of shut-in from WordNet
1
shut-in (adj.)
somewhat introverted;
Synonyms: introvertish
shut-in (adj.)
confined usually by illness;
Synonyms: homebound / housebound
2
shut-in (n.)
someone who is incapacitated by a chronic illness or injury;
Synonyms: invalid
From wordnet.princeton.edu