1570s, "sincere, honest" (a sense also in single-hearted); meaning "having a single aim or purpose" is from 1860. See single (adj.) + -minded. Related: Single-mindedly; single-mindedness.
single-minded in his determination to stop smoking
singe
singer
Singh
single
single-handed
single-minded
singlet
singleton
singly
sing-song
singspiel