smegma (n.)

sebaceous secretion, 1819, from Latin, from Greek smegma "a detergent, soap, unguent," from smekhein "to wipe off, wipe clean, cleanse," from PIE root *sme- "to smear" (source also of Czech smetana "cream," and see smear (v.)). So called from resemblance; a medical coinage, the word seems not to have been used in its literal Greek sense in English before this. Related: Smegmatic.