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sprain (n.)

c. 1600, of uncertain origin. The verb is attested from 1620s. A connection has been suggested to Middle French espraindre "to press out," from Latin exprimere [Klein, Century Dictionary], but the sense evolution is difficult. Related: Sprained; spraining.

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Definitions of sprain from WordNet
1
sprain (v.)
twist suddenly so as to sprain;
the hikers sprained their ankles when they fell
Synonyms: twist / wrench / turn / wrick / rick
2
sprain (n.)
a painful injury to a joint caused by a sudden wrenching of its ligaments;
From wordnet.princeton.edu