c. 1200, throwe "pain, pang of childbirth, agony of death," of uncertain origin, possibly from Old English þrawan "twist, turn, writhe" (see throw (v.)), or altered from Old English þrea (genitive þrawe) "affliction, pang, evil; threat, persecution" (related to þrowian "to suffer"), from Proto-Germanic *thrawo (source also of Middle High German dro "threat," German drohen "to threaten"). Modern spelling first recorded 1610s. Related: Throes.