1896, from Latin toti-, combining form of totus "whole" (see total (adj.)) + potent. Perhaps immediately from German totipotent, which is attested by 1893. Related: Totipotency.
embryonic stem cells are totipotent
totally
tote
totem
totemic
tother
totipotent
toto
toto caelo
totter
tottery
toucan