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transmutation (n.)

late 14c., from Old French transmutacion "transformation, change, metamorphosis" (12c.), from Late Latin transmutationem (nominative transmutatio) "a change, shift," noun of action from Latin transmutare "change from one condition to another," from trans "across, beyond; thoroughly" (see trans-) + mutare "to change" (from PIE root *mei- (1) "to change, go, move"). A word from alchemy.

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Definitions of transmutation from WordNet

transmutation (n.)
an act that changes the form or character or substance of something;
transmutation (n.)
a qualitative change;
Synonyms: transformation / shift
transmutation (n.)
(physics) the change of one chemical element into another (as by nuclear decay or radioactive bombardment);
the transmutation of base metals into gold proved to be impossible
From wordnet.princeton.edu