1787, of women, "unsuited to home life," 1813, of animals, "not brought under control of humans," from un- (1) "not" + past participle of domesticate (v.). Undomestic "not caring for home life" is recorded from 1754.
It is undomesticated women that poison the sources of our sweetest comforts. It is undomesticated women that have houses without any order or arrangements, servants without discipline, and children without instruction; ["Reflections on the Dangers and Insufficiency of Boarding Schools, considered as a mode of Female Education," 1787]