1590s, "not furnished with a guard," from un- (1) "not" + guarded. Sense of "not on one's guard, not taking heed" is attested from 1630s.
an unguarded gate
his unguarded queen was open to attack
an unguarded remark
ungraceful
ungracious
ungrammatical
ungrateful
ungual
unguarded
unguent
unguided
ungulate
unhallowed
unhampered