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unsex (v.)

"deprive of the qualities considered typical of one's gender," c. 1600, from un- (2) "reverse, opposite of" + sex (n.). Related: Unsexed; unsexing.

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Definitions of unsex from WordNet

unsex (v.)
deprive of sex or sexual powers;
unsex (v.)
remove the qualities typical of one's sex;
She unsexed herself
unsex (v.)
make infertile;
Synonyms: sterilize / sterilise / desex / desexualize / desexualise / fix
From wordnet.princeton.edu