"small cavity or vesicle," 1853, from French vacuole, from Medieval Latin vacuola, formed as a diminutive of Latin vacuus "empty," from PIE *wak-, extended form of root *eue- "to leave, abandon, give out."
vaccination
vaccine
vacillate
vacillation
vacuity
vacuole
vacuous
vacuum
vade
vade-mecum
vae victis
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