early 15c., "spiritual calling," from Old French vocacion "call, consecration; calling, profession" (13c.) or directly from Latin vocationem (nominative vocatio), literally "a calling, a being called" from vocatus "called," past participle of vocare "to call," which is related to vox (genitive vocis) "voice" (from PIE root *wekw- "to speak"). Sense of "one's occupation or profession" is first attested 1550s.