Old English wired "made of wire," past-participle adjective from wire (v.). From early 15c. as "stiffened by wires." Meaning "nervous, jittery" is by 1970s; earlier (1959, perhaps early 1950s) "using narcotic drugs, addicted to drugs."
a well-wired house
wired bundles of newspapers
wintry
wipe
wipeout
wiper
wire
wired
wiredraw
wiregrass
wireless
wireman
wire-tapping