1520s, "distorted, somewhat twisted to one side," from obsolete verb wry "to contort, to twist or turn," from Old English wrigian "to turn, bend, move, go," from Proto-Germanic *wrig- (source also of Old Frisian wrigia "to bend," Middle Low German wrich "turned, twisted"), from PIE *wreik- "to turn" (source also of Greek rhoikos "crooked," Lithuanian raišas "lame, limping"), from root *wer- (2) "to turn, bend." Of words, thoughts, etc., from 1590s. The original sense is preserved in awry.