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THYMOL, C

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Originally appearing in Volume V26, Page 905 of the 1911 Encyclopedia Britannica.
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THYMOL, C ,oH,4O or C6H3(OH) (See also:CH3) (C3Hr) [ 1 : 3: 6 ], a methylisopropylphenol isomeric with See also:carvacrol (q.v.), is an aromatic substance found with the See also:hydrocarbons cymene, C1oH,4, and thymene, Clean, in oil of See also:thyme (from Thymus vulgaris) and in other essential See also:oils, e.g. Carum copticum, from which it may be extracted by shaking with See also:potassium hydroxide, filtering and precipitating the phenol with hydrochloric See also:acid. It can be prepared from dibrom-menthone (obtained by brominating menthone in See also:chloroform See also:solution) by eliminating two molecules of hydrobromic acid. Thymol crystallizes in large colourless plates, which melt at 440 and See also:boil at 230°. On See also:distillation with See also:phosphorus sulphide it gives cymene. Thymol has a strong odour of thyme and a pungent See also:taste, and is freely soluble in See also:alcohol, See also:ether, chloroform or See also:olive oil, but almost insoluble in See also:cold See also:water. It is a more powerful antiseptic than carbolic acid, but its insolubility prevents its being used for the same purposes. A saturated solution (1 in loon of warm water), thymol See also:gauze and an ointment are used. Externally it is See also:anti-parasitic, and is used in certain stages of See also:eczema and See also:psoriasis, and the alcoholic solution has been used in See also:ringworm; internally it has been employed as an intestinal antiseptic in typhoid See also:fever. Its See also:chief use is as an anthelmintic to destroy the Ankylostoma duodenale. Thymol may See also:colour the urine See also:green. Thymol iodide, See also:official in the See also:United States, is a See also:compound of See also:iodine and thymol; it is also known as aristol or annidalin.

It was introduced as a substitute for See also:

iodoform and is stated to be less toxic. Glycothymolin is a proprietary preparation, used in the treatment of catarrhal conditions of mucous membranes, while a mixture of See also:naphthalene, camphor and thymol is sold under the name of thymolin.

End of Article: THYMOL, C

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