late 14c., "vapor, odorous vapor; exhalation," from Old French fum "smoke, steam, vapor, breath, aroma, scent" (12c.), from Latin fumus "smoke, steam, fume, old flavor" (source also of Italian fumo, Spanish humo), from PIE root *dheu- (1) "dust, vapor, smoke."
In old medicine, an "exhalation" of the body that produces emotions, dreams, sloth, etc; later especially of smokes or vapors that go to the head and affect the senses with a narcotic or stifling quality.