before vowels orth-, word-forming element meaning "straight, upright, rectangular, regular; true, correct, proper," now mostly in scientific and technical compounds, from Greek orthos "straight, true, correct, regular," from PIE *eredh- "high" (source also of Sanskrit urdhvah "high, lofty, steep," Latin arduus "high, steep," Old Irish ard "high").

word-forming element meaning variously "above; highest; across; higher in power or authority; too much; above normal; outer; beyond in time, too long," from Old English ofer (from PIE root *uper "over"). Over and its Germanic relations were widely used as prefixes, and sometimes could be used with negative force. This is rare in Modern English, but compare Gothic ufarmunnon "to forget," ufar-swaran "to swear falsely;" Old English ofercræft "fraud."

In some of its uses, moreover, over is a movable element, which can be prefixed at will to almost any verb or adjective of suitable sense, as freely as an adjective can be placed before a substantive or an adverb before an adjective. [OED]

Among the old words not now existing are Old English oferlufu (Middle English oferlufe), literally "over-love," hence "excessive or immoderate love." Over- in Middle English also could carry a sense of "too little, below normal," as in over-lyght "of too little weight" (c. 1400), overlitel "too small" (mid-14c.), overshort, etc.

phrase preceded by one, two, three, etc., and signifying the time of day as shown by the face of a clock, c. 1720, an abbreviation of of the clock, from Middle English of the clokke (late 14c.). See O + clock (n.). The use of clock hand positions to describe vector directions or angles is from late 18c.

1620s, auf, oph (modern form from 1630s; oafish is from 1610s), "a changeling; a foolish or otherwise defective child left by the fairies in place of another carried off," from a Scandinavian source such as Norwegian alfr "silly person," in Old Norse "elf" (see elf). Hence, "a misbegotten, deformed idiot, a simpleton" (17c.). Until recently, some dictionaries still gave the plural as oaves.