word-forming element expressing direction toward or in addition to, from Latin ad "to, toward" in space or time; "with regard to, in relation to," as a prefix, sometimes merely emphatic, from PIE root *ad- "to, near, at."

Simplified to a- before sc-, sp- and st-; modified to ac- before many consonants and then re-spelled af-, ag-, al-, etc., in conformity with the following consonant (as in affection, aggression). Also compare ap- (1).

In Old French, reduced to a- in all cases (an evolution already underway in Merovingian Latin), but written forms in French were refashioned after Latin in 14c. and English did likewise 15c. in words it had picked up from Old French. In many cases pronunciation followed the shift. Over-correction at the end of the Middle Ages in French and then English "restored" the -d- or a doubled consonant to some words that never had it (accursed, afford). The process went further in England than in France, where the vernacular sometimes resisted the pedantic, resulting in English adjourn, advance, address, advertisement (Modern French ajourner, avancer, adresser, avertissement). In modern word-formation sometimes ad- and ab- are regarded as opposites, but this was not in classical Latin.

scientific word-forming element meaning "gland," from Greek adēn "gland," probably from a suffixed form of PIE root *engw- "groin; internal organ" (source also of Latin inguen "groin;" see inguinal).

word-forming element meaning "air, atmosphere; gases," in 20c. use with reference to aircraft or aviation, from Greek aēr (genitive aeros) "air, lower atmosphere" (see air (n.1)).

word-forming element meaning "pertaining to agriculture or cultivation," from Greek agros "field," from PIE root *agro- "field."

word-forming element meaning "other," from Greek allos "other, different," cognate with Latin alius "other," from PIE root *al- (1) "beyond."