1650s, with -ity + Medieval Latin ambidexter, literally "right-handed on both sides," from ambi- "both, on both sides" (see ambi-) + dexter "right-handed" (from PIE root *deks- "right; south").
amber
ambergris
*ambhi-
ambi-
ambiance
ambidexterity
ambidextrous
Ambien
ambience
ambient
ambiguity