"section of something made by a plane passing through it at a right angle to one of its axes," 1748, originally in engineering sketches, from cross (adj.) + section (n.). Figurative sense of "representative sample" is by 1903.
cross-section views of the neck
cross-pollination
cross-purpose
cross-reference
crossroad
crossroads
cross-section
cross-stitch
cross-street
cross-tie
cross-town
crosswalk