"treat as unworthy of regard or notice," 1640s, from dis- + regard. Related: Disregarded; disregarding. As a noun, "failure to regard or notice," from 1660s. Related: Disregardful.
disqualification
disqualify
disquiet
disquietude
disquisition
disregard
disrelish
disremember
disrepair
disreputable
disrepute