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emasculate (v.)

"to deprive of the male functions, deprive of virility or procreative power," c. 1600, from Latin emasculatus, past participle of emasculare "castrate," from assimilated form of ex "out, away" (see ex-) + masculus "male, manly" (see masculine). Originally and usually in a figurative sense in English. Related: Emasculated; emasculating.

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Definitions of emasculate from WordNet
1
emasculate (v.)
deprive of strength or vigor;
The Senate emasculated the law
Synonyms: castrate
emasculate (v.)
remove the testicles of a male animal;
Synonyms: castrate / demasculinize / demasculinise
2
emasculate (adj.)
having unsuitable feminine qualities;
Synonyms: effeminate / epicene / cissy / sissified / sissyish / sissy
From wordnet.princeton.edu