"incapable of being satisfied or appeased; inordinately greedy," early 15c., insaciable, from Old French insaciable "ravenous" (15c., Modern French insatiable), or directly from Latin insatiabilis "not to be satisfied," from in- "not, opposite of" (from PIE root *ne- "not") + satiabilis, from satiare "fill full, satisfy," from satis "enough" (from PIE root *sa- "to satisfy"). Related: Insatiably; insatiableness.