"disreputable, vulgar," 1794, from low (adj.) + life (n.). As a noun, also lowlife, "coarse, no-good person," from 1911. Low-lived (adj.) is attested from 1760.
Lowestoft
low-grade
lowing
low-key
lowland
low-life
lowliness
lowly
low-minded
lowness
low-profile