"obstinately attached to one's opinion," 1590s, past-participle adjective from opiniate (1620s) "maintain dogmatically or obstinately" (from Latin opinio "opinion"), a verb once used where now we use opine. Also see opinionated.
ophthalmology
ophthalmoscope
opiate
opine
opiniaster
opiniated
opinion
opinionate
opinionated
opioid
opisthography