pill (n.)

c. 1400, pille, "globular or ovoid mass of medicinal substance of a size convenient for swallowing," from Middle Dutch or Middle Low German pille and Old French pile, all from Latin pilula "pill," literally "little ball," diminutive of pila "a ball, playing ball," which is perhaps related to pilus "hair" if the original notion was "hairball."

The figurative sense "something disagreeable that must be accepted ('swallowed')" is from 1540s. The slang meaning "disagreeable or objectionable person, bore," is by 1871. The pill "contraceptive pill" is from 1957.

1736, "to dose on pills," from pill (n.). From 1882 as "to form into pills." In club slang, "to reject by vote, blackball" (1855). Related: Pilled; pilling.

"deprive of hair, make bald," c. 1400, from late Old English, from Old French piller, from Latin pilare "to peel strip, deprive of hair," from pilus "hair" (see pile (n.3)). Now displaced by peel.