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regret (v.)

"to look back with distress or sorrowful longing; to grieve for on remembering," late 14c., from Old French regreter "long after, bewail, lament someone's death; ask the help of" (Modern French regretter), from re-, intensive prefix (see re-), + -greter, possibly from Frankish or some other Germanic source (compare Old English grætan "to weep;" Old Norse grata "to weep, groan"), from Proto-Germanic *gretan "weep." "Not found in other Romance languages, and variously explained" [Century Dictionary].

Related: Regretted; regretting. Replaced Old English ofþyncan, from of- "off, away," here denoting opposition, + þyncan "seem, seem fit" (as in methinks).

regret (n.)

"pain or distress in the mind at something done or left undone," 1530s, from the verb, or from Middle French regret, back-formation from regreter (see regret (v.)).

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Definitions of regret from WordNet
1
regret (v.)
feel remorse for; feel sorry for; be contrite about;
Synonyms: repent / rue
regret (v.)
feel sad about the loss or absence of;
regret (v.)
decline formally or politely;
I regret I can't come to the party
regret (v.)
express with regret;
I regret to say that you did not gain admission to Harvard
2
regret (n.)
sadness associated with some wrong done or some disappointment;
he wrote a note expressing his regret
Synonyms: sorrow / rue / ruefulness
From wordnet.princeton.edu