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INDOLE

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Originally appearing in Volume V14, Page 500 of the 1911 Encyclopedia Britannica.
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INDOLE , or BENioPYRR0I., CBH,N, a substance first prepared by A. See also:

Baeyer in 1868. It may be synthetically obtained by distilling oxindole (C8H8NO) with See also:zinc dust; by See also:heating orthonitrocinnamic See also:acid with potash and See also:iron filings; by the reduction of See also:indigo See also:blue; by the See also:action of See also:sodium ethylate on orthoaminochlorstyrene; by boiling-See also:aniline with dichloracetaldehyde; by the dry See also:distillation of ortho-tolyloxamic acid; by heating aniline with dichloracetal; by distilling a mixture of See also:calcium See also:INDORE formate and calcium anilidoacetate; and by heating pyruvic acid phenyl See also:hydrazone with anhydrous zinc chloride. It is also formed in the pancreatic See also:fermentation of albumen, and, in small quantities, by passing the vapours of mono- and dialkylanilines through a red-hot See also:tube. It crystallizes in shining leaflets, which melt at 52° C. and See also:boil at 245° C. (with decomposition), and is volatile in a current of See also:steam. It is a feeble See also:base, and gives a See also:cherry-red coloration with a See also:pine shaving. Many derivatives of indole are known. B-methyl indol or skatole occurs in human faeces.

End of Article: INDOLE

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