c. 1200, "physical comfort, undisturbed state of the body; tranquility, peace of mind," from Old French aise "comfort, pleasure, well-being; opportunity," which is of uncertain origin. According to Watkins is ultimately from Latin adiacens "lying at," present participle of adiacere "lie at, border upon, lie near," from ad "to" (see ad-) + iacere "to lie, rest," literally "to throw" (from PIE root *ye- "to throw, impel"). Recent dictionaries in English and French seem to support this derivation, though older sources found objections to it. Compare adagio.
At ease "at rest, at peace, in comfort" is from late 14c.; as a military order (1802) the word denotes "freedom from stiffness or formality."