1880, from Italian ptomaina, coined by Professor Francesco Selmi of Bologna, 1878, from Greek ptoma "corpse," on notion of poison produced in decaying matter. Greek ptoma is literally "a fall, a falling," via the notion of "fallen thing, fallen body;" nominal derivative of piptein "to fall" (from PIE *pi-pt-, reduplicated form of root *pet- "to rush; to fly"). Incorrectly formed, and Selmi is roundly scolded for it in OED, which says proper Greek would be *ptomatine.