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CINNOLIN, CRH6N2

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Originally appearing in Volume V06, Page 377 of the 1911 Encyclopedia Britannica.
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CINNOLIN, CRH6N2 , a See also:compound isomeric with phthalazine, prepared by boiling dihydrocinnolin dissolved in See also:benzene with freshly precipitated mercuric See also:oxide. The See also:solution is filtered and the hydrochloride of the See also:base precipitated by alcoholic hydrochloric See also:acid; the See also:free base is obtained as an oil by adding See also:caustic soda. It may be obtained in See also:white silky needles, melting at 24-25° C. and containing a See also:molecule of See also:ether of See also:crystallization by cooling the oil dissolved in ether. The free base melts at 39° C. It is a strong base, forming See also:stable salts with See also:mineral acids, and is easily soluble in See also:water and in the See also:ordinary organic solvents. It has a See also:taste resembling that of See also:chloral See also:hydrate, and leaves a See also:sharp irritation for some See also:time on the See also:tongue; it is also very poisonous (M. See also:Busch and A. Rast, Berichte, 1897, 30, p. 521). Cinnolin derivatives are obtained from oxycinnolin carboxylic acid, which is formed by digesting orthophenyl propiolic acid diazo chloride with water. Oxycinnolin carboxylic acid on See also:heating gives oxycinnolin, melting at 2250, which with See also:phosphorus pentachloride gives chlorcinnolin. This substance is reduced by See also:iron filings and sulphuric acid to dihydrocinnolin.

End of Article: CINNOLIN, CRH6N2

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