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MORTIFICATION , a See also: term used in See also:pathology and See also:surgery, signifying a See also:local See also:death (See also:Lat. mors) in the See also:animal See also:body. A portion of the body may See also:die in consequence of the disturbance of its See also:nutrition by inflammation, or of a cutting off of the See also:blood-See also:supply, as by pressure 'upon, or injury to, the blood-vessels. A comparatively slight injury affecting a portion of the body imperfectly supplied with blood may give rise to an inflammatory See also:condition which in a healthy See also:part might pass unnoticed, but which, in consequence of imperfect nutrition, may end in mortification. If the flow of arterial blood only is arrested, the part depending upon it for nutrition becomes numb, See also:cold and shrivelled, and the See also:form of mortification known as dry See also:gangrene occurs. This is See also:apt to be met with in oldish persons with diseased vessels and feeble See also:heart-See also:action, especially if the blood is rendered less nutritious by the presence of See also:diabetes or of See also:kidney disease. The See also:rule of treatment in all cases of threatened mortification is to keep the part warm by See also:flannel or See also:cotton-See also:wool, but to avoid all methods which unduly See also:hurry the returning circulation. Such increase would give rise to excessive reaction, which, in tissues already weakened, might actually produce mortification. When the part is dead it should be wrapped up in dry antiseptic dressings to prevent putrefaction. The surgeon should then wait until the " See also:line of demarcation," a linear ulceration, between the living and the dead part is evident, and then, if the See also:case permits, should amputate at a higher level. In spreading gangrene, in which acute See also:sepsis is See also:present, and in which no line of demarcation forms, the best See also:chance for the patient is promptly to amputate high up in See also:sound tissues. In these cases the blood is generally poisoned, and if the patient recovers from the See also:primary See also:shock of the operation, the disease may reappear in the stump, and See also:lead to a fatal result. See also:Frost-bite.—Under the See also:influence of cold, the blood-vessels See also:contract, and less blood is conveyed to the tissues.Frost-bite is particularly apt to attack the feet, the hands, and the tips of the ears. The condition is unassociated with See also:
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