Online Encyclopedia

Search over 40,000 articles from the original, classic Encyclopedia Britannica, 11th Edition.

PURPURA

Online Encyclopedia
Originally appearing in Volume V22, Page 665 of the 1911 Encyclopedia Britannica.
Spread the word: del.icio.us del.icio.us it!

PURPURA , in See also:

pathology, a See also:general See also:term for the symptom of See also:purple-coloured spots upon the See also:surface of the See also:body, due to extravasations of See also:blood in the skin, accompanied occasionally with haemorrhages from mucous membranes. The varieties of purpura may be conveniently divided as follows: (a) toxic, following the See also:administration of certain drugs, notably See also:copaiba, See also:quinine, See also:ergot, See also:belladonna and the iodides; also following snake-bite; (b) cachectic, seen in persons suffering from such diseases as See also:tuberculosis, See also:heart disease, See also:cancer, See also:Bright's disease, See also:jaundice, as well as from certain of the infectious fevers, extravasations of the See also:kind above mentioned being not infrequently See also:present; (c) neurotic; (d) arthritic, which includes the See also:form known as " Purpura simplex," in which there may or may not be articular See also:pain, and the complaint is usually ushered in by lassitude and feverishness, followed by the See also:appearance on the surface of the body of the characteristic spots in the form of small red points scattered over the skin of the limbs and See also:trunk. The spots are not raised above the surface, and they do not disappear on pressure. Their See also:colour soon becomes deep purple or nearly See also:black; but after a few days they undergo the changes which are observed in the See also:case of an See also:ordinary bruise, passing to a See also:green and yellow See also:hue and finally disappearing. When of See also:minute See also:size they are termed "petechiae" or " stigmata," when somewhat larger " vibices," and when in patches of considerable size " ecchymoses." They may come out in fresh crops over a lengthened See also:period. Purpura rheumatica (Schonlein's disease) is a remarkable variety characterized by sore See also:throat, See also:fever and articular pains accompanied by purpuric spots and associated with urticaria and occasionally with definite nodular infiltrations. This is by many writers considered to be a See also:separate disease, but it is usually regarded as of rheumatic origin. Purpura haemorrhagica (acute haemorrhagic purpura) is a more serious form, in which, in addition to the phenomena already mentioned as affecting the skin, there is a tendency to the occurrence of See also:haemorrhage from mucous surfaces, especially from the See also:nose, but also from the mouth, lungs, See also:stomach, bowels, kidneys, &c., sometimes in large and dangerous amount. See also:Great See also:physical prostration is See also:apt to attend this form of the disease, and a fatal result some-times follows the successive haemorrhages, or is suddenly precipitated by the occurrence of an extravasation of blood into the See also:brain. (see above) by the See also:action of aqueous See also:ammonia at 15o° C. It also results instead of the expected 7-methyl-2-oxy-6-aminopurin, when 7-methyl-6-amino-2-chlorpurin is treated with dilute alkalis (E. See also:Fischer, Ber., 1898, 31, p.

542), owing to See also:

ring splitting in the 1.6-position, followed by eliminating of halogen See also:acid. Thiopurins.—W. Traube (See also:Ann., 1904, 331, pp. 66 seq.) has obtained many compounds of the See also:purin See also:group by using thiourea, which is condensed with cyanacetic ester, &c., to form thiopyrimidines.

End of Article: PURPURA

Additional information and Comments

There are no comments yet for this article.
» Add information or comments to this article.
Please link directly to this article:
Highlight the code below, right click, and select "copy." Then paste it into your website, email, or other HTML.
Site content, images, and layout Copyright © 2006 - Net Industries, worldwide.
Do not copy, download, transfer, or otherwise replicate the site content in whole or in part.

Links to articles and home page are always encouraged.

[back]
PURPLE
[next]
PURRAH, PURROII