Search over 40,000 articles from the original, classic Encyclopedia Britannica, 11th Edition.
ELATERIUM , a See also:drug consisting of a sediment deposited by the juice of the See also:fruit of Ecballium Elaterium, the squirting See also:cucumber, a native of the Mediterranean region. The plant, which is a member of the natural See also:order See also:Cucurbitaceae, resembles the See also:vegetable marrow in its growth. The fruit resembles a small cucumber, and when ripe is highly turgid, and separates almost at a See also:touch from the fruit stalk. The end of the stalk forms a stopper, on the removal of which the fluid contents of the fruit, together with the seeds, are squirted through the See also:aperture by the sudden contraction of the See also:wall of the fruit. To prepare the drug the fruit is sliced lengthwise and slightly pressed; the greenish and slightly turbid juice thus obtained is strained and set aside; and the See also:deposit of elaterium formed after a few See also:hours is collected on a See also:linen See also:filter, rapidly drained, and dried on porous tiles at a See also:gentle See also:heat. Elaterium is met with in See also:commerce in See also:light, thin, friable, See also:flat or slightly incurved opaque cakes, of a greyish-See also:green See also:colour, See also:bitter See also:taste and See also:tea-like See also:smell. The drug is soluble in See also:alcohol, but insoluble in See also:water and See also:ether. The See also:official dose is io-2 See also:grain, and the See also:British pharmacopeia directs that the drug is to contain from 20 to 25% of the active principle elaterinum or elaterin. A See also:resin in the natural product See also:aids its See also:action. Elaterin is extracted from elaterium by See also:chloroform and then precipitated by ether. It has the See also:formula C2oH28Os. It forms colourless scales which have a bitter taste, but it is highly inadvisable to taste either this substance or elaterium. Its dose is iv- I s grain, and the British pharmacopeia contains a useful preparation, the Pulvis Elaterini Compositus, which contains one See also:part of the active principle in See also:forty. The action of this drug resembles that of the saline aperients, but is much more powerful. It is the most active hydragogue purgative known, causing also much depression and violent griping. When injected subcutaneously it is inert, as its action is entirely dependent upon its admixture with the bile. The drug is undoubtedly valuable in cases of See also:dropsy and See also:Bright's disease, and also in cases of cerebral See also:haemorrhage, threatened or See also:present. It must not be used except in urgent cases, and must invariably be employed with the utmost care, especially if the See also:state of the See also:heart be unsatisfactory. Additional information and CommentsThere are no comments yet for this article.
» Add information or comments to this article.
Please link directly to this article:
Highlight the code below, right click, and select "copy." Then paste it into your website, email, or other HTML. Site content, images, and layout Copyright © 2006 - Net Industries, worldwide. |
|
[back] ELATERITE |
[next] ELBA (Gr. AiWaXla; Lat. Ilva) |