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ARAROBA POWDER

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Originally appearing in Volume V02, Page 320 of the 1911 Encyclopedia Britannica.
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ARAROBA See also:

POWDER , a See also:drug occurring in the See also:form of a yellowish-See also:brown powder, varying considerably in tint, which derives an alternative name—Goa powder—from the Portuguese See also:colony of See also:Goa, where it appears to have been introduced about the See also:year 1852. The See also:tree which yields it is the Andira Araroba of the natural See also:order See also:Leguminosae. It is met with in See also:great abundance in certain forests in the See also:province of See also:Bahia, preferring as a See also:rule See also:low and humid spots. The tree is from 8o to Too ft. high and has large imparipinnate leaves, the leaflets of which are oblong, about 12 in. See also:long and a in. broad, and somewhat truncate at the See also:apex. The See also:flowers are papilionaceous, of a See also:purple See also:colour and arranged in panicles. The Goa powder or araroba is contained in the See also:trunk, filling crevices in the heartwood. It is a morbid product in the tree, and yields to hot See also:chloroform 5o% of a substance known officially as chrysarobin, which has a definite therapeutic value and is contained in most See also:modern pharmacopoeias. It occurs as a micro-crystalline, odourless, tasteless powder, very slightly soluble in either See also:water or See also:alcohol; it also occurs in See also:rhubarb See also:root. This complex mixture contains pure chrysarobin (C15H1203), di-chrysarobin methylether (C36H2307.00H3), di-chrysarobin (C30Hu07). Chrysarobin is a methyl trioxyanthracene and exists as a See also:glucoside in the plant, but is gradually oxidized to chrysophanic See also:acid (a dioxy-methyl See also:anthraquinone) and See also:glucose. This strikes a See also:blood-red colour in alkaline solutions, and may therefore cause much alarm if administered to a patient whose urine is alkaline. The See also:British See also:pharmacopoeia has an ointment containing one See also:part of chrysarobin and 24 of benzoated See also:lard.

Both internally and externally the drug is a powerful irritant. The See also:

general practice amongst modern dermatologists is to use only chrysephanic acid, which may be applied externally and given by the mouth in doses of about one See also:grain in cases of See also:psoriasis and chronic See also:eczema. The drug is a feeble parasiticide, and has been used locally in the treatment of See also:ringworm. It stains the skin—and linen—a deep yellow or brown, a coloration which may be removed by See also:caustic See also:alkali in weak See also:solution.

End of Article: ARAROBA POWDER

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