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NUR VOMICA

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Originally appearing in Volume V19, Page 928 of the 1911 Encyclopedia Britannica.
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NUR VOMICA , a poisonous See also:

drug, consisting of the See also:seed of Sirychnos Nux-Vomica, a See also:tree belonging to the natural See also:order Loganiaceae, indigenous to most parts of See also:India, and found also in See also:Burma, See also:Siam, See also:Cochin See also:China and See also:northern See also:Australia. The tree is of moderate See also:size, with a See also:short, thick, often crooked, See also:stem, and ovate entire leaves, marked with three to five See also:veins radiating from the See also:base of the See also:leaf. The See also:flowers are small, greenish-See also:white and tubular, and are arranged in terminal corymbs. The See also:fruit is of the size of a small See also:orange, and has a thin hard See also:shell, enclosing a See also:bitter, gelatinous white pulp, in which from i to 5 seeds are vertically embedded. The seed is disk-shaped, rather less than 1 in. in See also:diameter, and about f in. in thickness, slightly depressed towards the centre, and in some varieties furnished with an acute See also:keel-like See also:ridge at the margin. The See also:external See also:surface of the seed is of a greyish-See also:green See also:colour and satiny See also:appearance, due to a coating of appressed silky hairs. The interior of the seed consists chiefly of horny albumen, which is easily divided along its See also:outer edge into halves by a fissure, in which lies the embryo. The latter is about in. See also:long, and has a pair of See also:heart-shaped membranous cotyledons. The See also:chief constituents of the seeds are the alkaloids See also:strychnine (q.v.) and See also:brucine, the former averaging about o•4%, and the latter about See also:half this amount. The seeds also contain an See also:acid, strychnic or igasuric acid; a See also:glucoside, loganin; See also:sugar and See also:fat. The dose of the seeds is s to 4 grains. The See also:British See also:Pharmacopoeia contains three preparations of nux vomica.

The liquid See also:

extract is standardized to contain 1.5% of strychnine; the extract is standardized to contain 5%; and the See also:tincture, which is the most widely used, is standardized to contain o•25%. The See also:pharmacology of nux vomica is practically that of strychnine. The tincture is chiefly used in cases of atonic See also:dyspepsia, and is See also:superior to all other bitter tonics, in that it is antiseptic and has a more powerful See also:action upon the movements of the gastric See also:wall. The extract is of See also:great value in the treatment of See also:simple See also:constipation.

End of Article: NUR VOMICA

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