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See also:JALISCO, XALISCO , Or See also:GUADALAJARA, a Pacific See also:coast See also:state of See also:Mexico, of very irregular shape, bounded, beginning on the N., by the territory of See also:Tepic and the states of See also:Durango, See also:Zacatecas, Aguas Calientes, See also:Guanajuato, See also:Michoacan, and See also:Colima. Pop. (1900), 1,153,891. See also:Area, 31,846 sq. m. Jalisco is traversed from N.N.W. to S.S.E. by the Sierra Madre, locally known as the Sierra de Nayarit and Sierra de Jalisco, which divides the state into a See also:low heavily forested coastal • See also:plain and a high See also:plateau region, See also:part of the See also:great See also:Anahuac table-See also:land, with an See also:average See also:elevation of about 5000 ft., broken by spurs and flanking ranges of moderate height. The sierra region is largely volcanic and earthquakes are frequent; in the S. are the active volcanoes of Colima (12,750 ft.) and the Nevado de Colima (14,363) ft.). The tierra caliente See also:zone of the coast is tropical, humid, and unfavourable to Europeans, while the inland plateaus vary from sub-tropical to temperate and are generally drier and healthful. The greater part of the state is drained by the Rio Grande de See also:Lerma (called the See also:Santiago on its See also:lower course) and its tributaries, See also:chief of which is the Rio Verde. Lakes are numerous; the largest are the Chapala, about 8o m. See also:long by to to 35 M. wide, which is considered one of the most beautiful inland sheets of See also:water in Mexico, the Sayula and the Magdalena, noted for their abundance of See also:fish. The agricultural products of Jalisco include See also:Indian See also:corn, See also:wheat and beans on the uplands, and See also:sugar-See also:cane, See also:cotton, See also:rice, See also:indigo and See also:tobacco in the warmer districts. See also:Rubber and See also:palm oil are natural See also:forest products of the coastal zone. Stock-raising is an important occupation in some of the more elevated districts. The See also:mineral resources include See also:silver, See also:gold, See also:cinnabar, See also:copper, See also:bismuth, and various See also:precious stones. There are reduction See also:works of the old-fashioned type and some manufactures, including cotton and woollen goods, pottery, refined sugar and See also:leather. The commercial activities of the state contribute much to its prosperity. There is a large percentage of See also:Indians and mestizos in the See also:population. The See also:capital is Guadalajara, and other important towns with their populations in 'goo (unless otherwise stated) are: Zapotlanejo (20,275), 21 M. E. by N. of Guadalajara; See also:Ciudad Guzman (17,374 in 1895), 6o m. N.E. of Colima; See also:Lagos (14,716 in 1895), a See also:mining See also:town too m. E.N.E. of Guadalajara on the Mexican Central railway; Tamazula (8.783 in 1895); Sayula (7883); Autlan (7715); 'feocaltiche (8881); Ameca (7212 in 1895), in a fertile agricultural It grows in Mexico along the See also:mountain range of the Sierra Gorda in the neighbourhood of See also:San Luis de la Paz, from which See also:district it is carried down to See also:Tampico, whence it is exported. A third variety of See also:jalap known as woody jalap, male jalap, or See also:Orizaba See also:root, or by the Mexicans as Purgo macho, is derived from I pomaea orizabensis, a plant of Orizaba. The root occurs in fibrous pieces, which are usually rectangular blocks of irregular shape, 2 in. or more in See also:diameter, and are evidently portions of a large root. It is only occasionally met with in See also:commerce. The dose of jalap is from five to twenty grains, the See also:British Pharmacopeia directing that it must contain from 9 to II % of the See also:resin, which is given in doses of two to five grains. One preparation of this See also:drug is in See also:common use, the Pulvis Jalapae Compositus, which consists of 5 parts of jalap, 9 of cream of See also:tartar, and i of See also:ginger. The dose is from 20 grains to a drachm. It is best given in the maximum dose which causes the minimum of irritation. The chief constituents of jalap resin are two glucosides—convolvulin and jalapin—sugar, See also:starch and See also:gum. Convolvulin constitutes nearly 20 % of the resin. It is insoluble in See also:ether, and is more active than jalapin. It is not used separately in See also:medicine. Jalapin is See also:present in about the same proportions. It dissolves readily in ether, and has a soft resinous consistence. It may be given in See also:half-See also:grain doses. It is the active principle of the allied drug See also:scammony. According to See also:Mayer, the See also:formula of convolvulin is C34H60O16, and that of jalapin Ca1Hfi0Ois. Jalap is a typical hydragogue purgative, causing the See also:excretion of more fluid than scammony, but producing less stimulation of the See also:muscular See also:wall of the bowel. For both reasons it is preferable to scammony. It was shown by See also:Professor See also:Rutherford at See also:Edinburgh to be a powerful secretory cholagogue, an See also:action possessed by few hydragogue purgatives. The stimulation of the See also:liver is said to depend upon the See also:solution of the resin by the intestinal secretion. The drug is largely employed in cases of See also:Bright's disease and See also:dropsy from any cause, being especially useful when the liver shares in the See also:general venous congestion. It is not much used in See also:ordinary See also:constipation. 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